Restaurants are being destroyed. The authorities are clueless and New Yorkers are panicked. Moon-lighting as a baseball team, four talking dogs form a secret agancy called M.I.S.N.Y. (The Most Important Sniffers of New York) and take on the challenge of capturing the "Restaurant Marauder." They choose a special 12-year-old boy they name "D-Boy" (Dog-Boy) as their assistant, umpire and link to the human world. On their mission, they are befriended by a worldly, neighborhood butcher, a delusional man who believes he has a sixth sense and a savvy 12-year-old-girl whose curiosity lands her smack in the middle of it all. Their antics and adventures take them through a food ravaged New York as they attempt to put an end to the madness.